Gut Healing After NSAIDS

NSAIDS - Non-steroidal anti-inflammatories help to manage pain by blocking an enzyme called cyclooxygenase (COX) which the body uses to make prostaglandins (inflammatory messenger).

Unfortunately, with any short term quick fix comes some longer term negative side effects.

NSAIDS physically damage the gut lining which causes leaky gut leading to more inflammation.

Some side effects of NSAIDS include:
🔸Stomach aches
🔸Stomach ulcers
🔸Headaches
🔸Drowsiness
🔸Allergic reactions

NSAIDS & Histamine
🥵 NSAID Hypersensitivity (NHS) is when an individual reacts to a dose which is likely due to already having elevated of levels of histamine in their body, a DAO deficiency or polymorphism of the DAO gene, or due to leaky gut.

NSAIDS are able to elicit the production of specific IgE antibodies which bind to the surface of mast cells, triggering them to release histamine. Someone can also have a polymorphism which the HMNT enzyme which breaks down histamine, causing excess levels.

So what can you do to mitigate the harmful effects if you have to take NSAIDS for pain relief?
🔸Take NAC along with the advil to give your liver a helping hand with detox
🔸Alpha lipoic acid is also helpful to boost liver function among long list of other benefits
🔸Vitamin C helps to rebuild collagen, soothing to the gut lining boosts immune system
🔸Chrollela is incredibly nutrient dense seaweed with powerful phytochemicals & amino acids for liver health
🔸Colostrum is nature's probiotics perfect for sensitive guts & is high in immune boosting compounds

I would also supplement with the DAO enzyme at the same time as taking NSAIDS to help break down excess histamine produced.